Integrin‐Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor‐Specific Delivery Achieve MYCN Silencing with Improved Survival

The authors aim to develop siRNA therapeutics for cancer that can be administered systemically to target tumors and retard their growth. The efficacy of systemic delivery of siRNA to tumors with nanoparticles based on lipids or polymers is often compromised by their rapid clearance from the circulat...

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Detalles Bibliográficos
Autores principales: Tagalakis, Aristides D., Jayarajan, Vignesh, Maeshima, Ruhina, Ho, Kin H., Syed, Farhatullah, Wu, Lin‐Ping, Aldossary, Ahmad M., Munye, Mustafa M., Mistry, Talisa, Ogunbiyi, Olumide Kayode, Sala, Arturo, Standing, Joseph F., Moghimi, Seyed M., Stoker, Andrew W., Hart, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178728/
https://www.ncbi.nlm.nih.gov/pubmed/35712226
http://dx.doi.org/10.1002/adfm.202104843

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