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Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile

[Image: see text] The pharmacodynamic profile of antimicrobial peptides (AMPs) and their in vivo synergy are two factors that are thought to restrict resistance evolution and ensure their conservation. The frog Rana temporaria secretes a family of closely related AMPs, temporins A–L, as an effective...

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Detalles Bibliográficos
Autores principales:	Ferguson, Philip M., Clarke, Maria, Manzo, Giorgia, Hind, Charlotte K., Clifford, Melanie, Sutton, J. Mark, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178791/ https://www.ncbi.nlm.nih.gov/pubmed/35609188 http://dx.doi.org/10.1021/acs.biochem.1c00762

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