Emerging roles for lncRNA-NEAT1 in colorectal cancer

Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular an...

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Autores principales: Azizidoost, Shirin, Ghaedrahmati, Farhoodeh, Anbiyaee, Omid, Ahmad Ali, Riyadh, Cheraghzadeh, Maryam, Farzaneh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178824/
https://www.ncbi.nlm.nih.gov/pubmed/35676702
http://dx.doi.org/10.1186/s12935-022-02627-6
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author Azizidoost, Shirin
Ghaedrahmati, Farhoodeh
Anbiyaee, Omid
Ahmad Ali, Riyadh
Cheraghzadeh, Maryam
Farzaneh, Maryam
author_facet Azizidoost, Shirin
Ghaedrahmati, Farhoodeh
Anbiyaee, Omid
Ahmad Ali, Riyadh
Cheraghzadeh, Maryam
Farzaneh, Maryam
author_sort Azizidoost, Shirin
collection PubMed
description Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular and translational medicine. Emerging evidence has supported that lncRNAs can regulate cell cycle of CRC cells. LncRNA NEAT1 has been verified to participate in colon cancer development and progression. NEAT1 as a competing endogenous RNA could suppress the expression of miRNAs, and then regulate molecules downstream of these miRNAs. In this review, we summarized emerging roles of NEAT1 in CRC cells.
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spelling pubmed-91788242022-06-10 Emerging roles for lncRNA-NEAT1 in colorectal cancer Azizidoost, Shirin Ghaedrahmati, Farhoodeh Anbiyaee, Omid Ahmad Ali, Riyadh Cheraghzadeh, Maryam Farzaneh, Maryam Cancer Cell Int Review Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular and translational medicine. Emerging evidence has supported that lncRNAs can regulate cell cycle of CRC cells. LncRNA NEAT1 has been verified to participate in colon cancer development and progression. NEAT1 as a competing endogenous RNA could suppress the expression of miRNAs, and then regulate molecules downstream of these miRNAs. In this review, we summarized emerging roles of NEAT1 in CRC cells. BioMed Central 2022-06-08 /pmc/articles/PMC9178824/ /pubmed/35676702 http://dx.doi.org/10.1186/s12935-022-02627-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Azizidoost, Shirin
Ghaedrahmati, Farhoodeh
Anbiyaee, Omid
Ahmad Ali, Riyadh
Cheraghzadeh, Maryam
Farzaneh, Maryam
Emerging roles for lncRNA-NEAT1 in colorectal cancer
title Emerging roles for lncRNA-NEAT1 in colorectal cancer
title_full Emerging roles for lncRNA-NEAT1 in colorectal cancer
title_fullStr Emerging roles for lncRNA-NEAT1 in colorectal cancer
title_full_unstemmed Emerging roles for lncRNA-NEAT1 in colorectal cancer
title_short Emerging roles for lncRNA-NEAT1 in colorectal cancer
title_sort emerging roles for lncrna-neat1 in colorectal cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178824/
https://www.ncbi.nlm.nih.gov/pubmed/35676702
http://dx.doi.org/10.1186/s12935-022-02627-6
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