CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway

BACKGROUND: The dynamic epigenome and proteins specialized in the interpretation of epigenetic marks critically contribute to leukemic pathogenesis but also offer alternative therapeutic avenues. Targeting newly discovered chromatin readers involved in leukemogenesis may thus provide new anticancer...

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Detalles Bibliográficos
Autores principales: Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Dell’Aversana, Carmela, Bove, Guglielmo, Benedetti, Rosaria, Montella, Liliana, Ciardiello, Fortunato, Carafa, Vincenzo, Ambrosino, Concetta, Tucci, Valeria, Conte, Mariarosaria, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178829/
https://www.ncbi.nlm.nih.gov/pubmed/35681235
http://dx.doi.org/10.1186/s12943-022-01603-y

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