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16-membered ring macrolides and erythromycin induce ermB expression by different mechanisms

BACKGROUND: Ribosome stalling on ermBL at the tenth codon (Asp) and mRNA stabilization are believed to be mechanisms by which erythromycin (Ery) induces ermB expression. Expression of ermB is also induced by 16-membered ring macrolides (tylosin, josamycin and spiramycin), but the mechanism underlyin...

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Detalles Bibliográficos
Autores principales: He, Weizhi, Jiang, Kai, Qiu, Hua, Liao, Lijun, Wang, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178857/
https://www.ncbi.nlm.nih.gov/pubmed/35681117
http://dx.doi.org/10.1186/s12866-022-02565-3

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