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New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair

Background  The “obesity paradox,” whereby the body mass index (BMI) mortality curve is “U-shaped,” is a well-studied phenomenon in vascular surgery. However, there has been an overreliance on BMI as the measure of obesity, which has shown to poorly correlate with clinical outcomes. Robust measures...

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Autores principales: Wall, Joshua John Sommerville, Boag, Katie F., Waduud, Mohammed A., Pabale, Keleabetswe, Wood, Benjamin, Bailey, Marc, Scott, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179208/
https://www.ncbi.nlm.nih.gov/pubmed/35640583
http://dx.doi.org/10.1055/s-0042-1742699
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author Wall, Joshua John Sommerville
Boag, Katie F.
Waduud, Mohammed A.
Pabale, Keleabetswe
Wood, Benjamin
Bailey, Marc
Scott, Julian A.
author_facet Wall, Joshua John Sommerville
Boag, Katie F.
Waduud, Mohammed A.
Pabale, Keleabetswe
Wood, Benjamin
Bailey, Marc
Scott, Julian A.
author_sort Wall, Joshua John Sommerville
collection PubMed
description Background  The “obesity paradox,” whereby the body mass index (BMI) mortality curve is “U-shaped,” is a well-studied phenomenon in vascular surgery. However, there has been an overreliance on BMI as the measure of obesity, which has shown to poorly correlate with clinical outcomes. Robust measures such as waist-hip ratio (WHR) have been suggested as a more accurate marker reflecting central obesity. Objectives  The objectives of this study were to evaluate the correlation between BMI and WHR on postoperative morbidity and mortality after elective abdominal aortic aneurysm (AAA) repair. Methods  Data were collected from the Leeds Vascular Institute between January 2006 and December 2016. The primary outcome was mortality and secondary outcomes included length of stay (LOS) and all-cause readmission. Binary logistic regression, linear regression, and correlation analysis were used to identify associations between BMI and WHR in relation to outcome measures. Results  After exclusions, 432 elective AAA repairs (281 open surgical repair [OSR] and 151 endovascular aneurysm repairs [EVARs]) were identified to be eligible for the study. The combined 30-day and 4-year mortality was 1.2 and 20.1%, respectively. The 30-day readmission rate was 3.9% and the average LOS was 7.33 (standard deviation 18.5) days. BMI data was recorded for 275 patients (63.7%) and WHR for 355 patients (82.2%). Logistic regression analysis highlighted no association between BMI and WHR with mortality, readmission, or LOS following OSR or EVAR. Conclusion  The results of this study suggest patients should not be denied treatment for AAA based on obesity alone.
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spelling pubmed-91792082022-06-10 New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair Wall, Joshua John Sommerville Boag, Katie F. Waduud, Mohammed A. Pabale, Keleabetswe Wood, Benjamin Bailey, Marc Scott, Julian A. Aorta (Stamford) Background  The “obesity paradox,” whereby the body mass index (BMI) mortality curve is “U-shaped,” is a well-studied phenomenon in vascular surgery. However, there has been an overreliance on BMI as the measure of obesity, which has shown to poorly correlate with clinical outcomes. Robust measures such as waist-hip ratio (WHR) have been suggested as a more accurate marker reflecting central obesity. Objectives  The objectives of this study were to evaluate the correlation between BMI and WHR on postoperative morbidity and mortality after elective abdominal aortic aneurysm (AAA) repair. Methods  Data were collected from the Leeds Vascular Institute between January 2006 and December 2016. The primary outcome was mortality and secondary outcomes included length of stay (LOS) and all-cause readmission. Binary logistic regression, linear regression, and correlation analysis were used to identify associations between BMI and WHR in relation to outcome measures. Results  After exclusions, 432 elective AAA repairs (281 open surgical repair [OSR] and 151 endovascular aneurysm repairs [EVARs]) were identified to be eligible for the study. The combined 30-day and 4-year mortality was 1.2 and 20.1%, respectively. The 30-day readmission rate was 3.9% and the average LOS was 7.33 (standard deviation 18.5) days. BMI data was recorded for 275 patients (63.7%) and WHR for 355 patients (82.2%). Logistic regression analysis highlighted no association between BMI and WHR with mortality, readmission, or LOS following OSR or EVAR. Conclusion  The results of this study suggest patients should not be denied treatment for AAA based on obesity alone. Thieme Medical Publishers, Inc. 2022-05-31 /pmc/articles/PMC9179208/ /pubmed/35640583 http://dx.doi.org/10.1055/s-0042-1742699 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Wall, Joshua John Sommerville
Boag, Katie F.
Waduud, Mohammed A.
Pabale, Keleabetswe
Wood, Benjamin
Bailey, Marc
Scott, Julian A.
New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title_full New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title_fullStr New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title_full_unstemmed New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title_short New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes after Elective Abdominal Aortic Aneurysm Repair
title_sort new measures, old conclusions: obesity does not worsen outcomes after elective abdominal aortic aneurysm repair
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179208/
https://www.ncbi.nlm.nih.gov/pubmed/35640583
http://dx.doi.org/10.1055/s-0042-1742699
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