The AKT1E17K Allele Promotes Breast Cancer in Mice

SIMPLE SUMMARY: The main finding reported in this manuscript is that the gain-of-function mutation AKT1E17K is a bona fide oncogene for mammary epithelium, being able to efficiently initiate breast cancer in mice. On the basis of high-molecular-weight cytokeratins expressed by AKT1E17K-derived tumor...

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Detalles Bibliográficos
Autores principales: Malanga, Donatella, Laudanna, Carmelo, Mirante, Teresa, Colelli, Fabiana, Migliozzi, Simona, Zoppoli, Pietro, Santamaria, Gianluca, Roberto, Luca, De Marco, Carmela, Scarfò, Marzia, Montanaro, Donatella, Paciello, Orlando, Papparella, Serenella, Mignogna, Chiara, Baldi, Alfonso, Viglietto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179273/
https://www.ncbi.nlm.nih.gov/pubmed/35681625
http://dx.doi.org/10.3390/cancers14112645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179273/
https://www.ncbi.nlm.nih.gov/pubmed/35681625
http://dx.doi.org/10.3390/cancers14112645

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