Cargando…

SAR131675, a VEGRF3 Inhibitor, Modulates the Immune Response and Reduces the Growth of Colorectal Cancer Liver Metastasis

SIMPLE SUMMARY: Colorectal cancer most often metastasizes to the liver, and in most cases, it is unresectable at diagnosis. New treatment options targeting specific cancer characteristics are needed and are currently being explored. Herein we looked at the use of a selective VEGFR-3 tyrosine kinase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walsh, Katrina A., Kastrappis, Georgios, Fifis, Theodora, Paolini, Rita, Christophi, Christopher, Perini, Marcos V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179346/ https://www.ncbi.nlm.nih.gov/pubmed/35681695 http://dx.doi.org/10.3390/cancers14112715

Ejemplares similares

Immunomodulatory effects of renin–angiotensin system inhibitors on T lymphocytes in mice with colorectal liver metastases
por: Vallejo Ardila, Dora Lucia, et al.
Publicado: (2020)

Captopril, a Renin–Angiotensin System Inhibitor, Attenuates Tumour Progression in the Regenerating Liver Following Partial Hepatectomy
por: Riddiough, Georgina E., et al.
Publicado: (2022)

Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis
por: Riddiough, Georgina E., et al.
Publicado: (2021)

The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model
por: da Costa, Patricia Luiza Nunes, et al.
Publicado: (2018)

Vascular disruptive agent OXi4503 and anti-angiogenic agent Sunitinib combination treatment prolong survival of mice with CRC liver metastasis
por: Nguyen, Linh, et al.
Publicado: (2016)

Renin-angiotensin inhibitors reprogram tumor immune microenvironment: A comprehensive view of the influences on anti-tumor immunity
por: Vallejo-Ardila, Dora L., et al.
Publicado: (2018)

Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastases
por: Lin, Wen Xu, et al.
Publicado: (2011)

The Hepatitis B Virus Pre-Core Protein p22 Activates Wnt Signaling
por: Tran, Bang Manh, et al.
Publicado: (2020)

Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice
por: Hwang, Seun Deuk, et al.
Publicado: (2019)

Specific Inhibition of the VEGFR-3 Tyrosine Kinase by SAR131675 Reduces Peripheral and Tumor Associated Immunosuppressive Myeloid Cells
por: Espagnolle, Nicolas, et al.
Publicado: (2014)

Advances in targeted and immunobased therapies for colorectal cancer in the genomic era
por: Seow, Heng Fong, et al.
Publicado: (2016)

Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments
por: Nguyen, Linh, et al.
Publicado: (2012)

The Prognostic Significance of Lymphatics in Colorectal Liver Metastases
por: Muralidharan, Vijayaragavan, et al.
Publicado: (2014)

Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor
por: Fifis, Theodora, et al.
Publicado: (2013)

Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
por: Ager, Eleanor I, et al.
Publicado: (2010)

Correction: Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
por: Ager, Eleanor I, et al.
Publicado: (2010)

Mechanisms of colorectal liver metastasis development
por: Shasha, Tal, et al.
Publicado: (2022)

Editorial: reducing blood loss in liver transplantation—the impact of surgical technique
por: Perini, Marcos V., et al.
Publicado: (2021)

Changes in the renin angiotensin system during the development of colorectal cancer liver metastases
por: Neo, Jaclyn H, et al.
Publicado: (2010)

HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis
por: Wada, Yuma, et al.
Publicado: (2020)

Hepatectomy and liver regeneration in the results of treatment of colorectal liver metastasis
por: Inoue, Yoshihiro, et al.
Publicado: (2020)

Pinworm infection masquerading as colorectal liver metastasis
por: Roberts, KJ, et al.
Publicado: (2012)

The surgical treatment of colorectal liver metastasis in the elderly
por: Donati, Marcello, et al.
Publicado: (2009)

T1 Colorectal Cancer with Synchronous Liver Metastasis
por: Sugimoto, Kiichi, et al.
Publicado: (2013)

Recent advances in treatment for colorectal liver metastasis
por: Oki, Eiji, et al.
Publicado: (2018)

Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer
por: Chan, Gloria, et al.
Publicado: (2020)

The role of the immunoescape in colorectal cancer liver metastasis
por: Takasu, Chie, et al.
Publicado: (2021)

PROTOCOL FOR LIVER TRANSPLANTATION IN UNRESECTABLE COLORECTAL METASTASIS
por: ERNANI, Lucas, et al.
Publicado: (2022)

Salmonella typhimurium: a rare cause of mesh-related infection
por: Sidhu, Ankur, et al.
Publicado: (2017)

High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer
por: Gaber, A, et al.
Publicado: (2009)

DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis
por: Konishi, Kazuo, et al.
Publicado: (2011)

IL-22BP controls the progression of liver metastasis in colorectal cancer
por: Giannou, Anastasios D., et al.
Publicado: (2023)

Granuloma Mimicking Local Recurrence on PET/CT after Liver Resection of Colorectal Liver Metastasis: A Case Report
por: Pantiora, Eirini V, et al.
Publicado: (2016)

ASO Author Reflections: The Prognostic Value of Time to Metastasis in Colorectal Liver Metastasis
por: Höppener, Diederik J., et al.
Publicado: (2019)

Reresection of Colorectal Liver Metastasis with Vena Cava Resection
por: Tardu, Ali, et al.
Publicado: (2016)

Literature Review of Current Management of Colorectal Liver Metastasis
por: Mitchell, Diana, et al.
Publicado: (2019)

microRNA biomarkers in colorectal cancer liver metastasis
por: Huang, Shulin, et al.
Publicado: (2018)

Repeat hepatectomy for recurred colorectal liver metastasis: is it justified?
por: Park, Jangho, et al.
Publicado: (2019)

Down-Regulation of Collagen Hydroxylation in Colorectal Liver Metastasis
por: van Huizen, Nick A., et al.
Publicado: (2020)

Colorectal Cancer Stem Cells in the Progression to Liver Metastasis
por: Gonzalez-Villarreal, Carlos A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1igfk134iibi10a0mt4132q0hi