Dysregulation of Immune Response Mediators and Pain-Related Ion Channels Is Associated with Pain-like Behavior in the GLA KO Mouse Model of Fabry Disease

Fabry disease (FD) is a rare life-threatening disorder caused by deficiency of the alpha-galactosidase A (GLA) enzyme with a characteristic pain phenotype. Impaired GLA production or function leads to the accumulation of the cell membrane compound globotriaosylceramide (Gb3) in the neurons of the do...

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Detalles Bibliográficos
Autores principales: Spitzel, Marlene, Wagner, Elise, Breyer, Maximilian, Henniger, Dorothea, Bayin, Mehtap, Hofmann, Lukas, Mauceri, Daniela, Sommer, Claudia, Üçeyler, Nurcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179379/
https://www.ncbi.nlm.nih.gov/pubmed/35681422
http://dx.doi.org/10.3390/cells11111730

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