Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response

Hyperosmolality can occur during industrial fed-batch cultivation processes of Chinese hamster ovary (CHO) cells as highly concentrated feed and base solutions are added to replenish nutrients and regulate pH values. Some effects of hyperosmolality, such as increased cell size and growth inhibition,...

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Detalles Bibliográficos
Autores principales: Romanova, Nadiya, Schmitz, Julian, Strakeljahn, Marie, Grünberger, Alexander, Bahnemann, Janina, Noll, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179406/
https://www.ncbi.nlm.nih.gov/pubmed/35681457
http://dx.doi.org/10.3390/cells11111763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179406/
https://www.ncbi.nlm.nih.gov/pubmed/35681457
http://dx.doi.org/10.3390/cells11111763

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