Exposed and Sequestered Antigens in Testes and Their Protection by Regulatory T Cell-Dependent Systemic Tolerance

Continuous exposure of tissue antigen (Ag) to the autoantigen-specific regulatory T cells (Treg) is required to maintain Treg-dependent systemic tolerance. Thus, testis autoantigens, previously considered as sequestered, may not be protected by systemic tolerance. We now document that the complete t...

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Detalles Bibliográficos
Autores principales: Harakal, Jessica, Qiao, Hui, Wheeler, Karen, Rival, Claudia, Paul, Alberta G. A., Hardy, Daniel M., Cheng, C. Yan, Goldberg, Erwin, Tung, Kenneth S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179417/
https://www.ncbi.nlm.nih.gov/pubmed/35693780
http://dx.doi.org/10.3389/fimmu.2022.809247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179417/
https://www.ncbi.nlm.nih.gov/pubmed/35693780
http://dx.doi.org/10.3389/fimmu.2022.809247

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