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Synergistic Tumor Inhibition via Energy Elimination by Repurposing Penfluridol and 2-Deoxy-D-Glucose in Lung Cancer
SIMPLE SUMMARY: Drug repurposing has been effective for discovering novel treatments for cancer. The antipsychotic agent penfluridol was reported to suppress lung cancer growth via ATP energy deprivation. The aim of our study was to investigate how penfluridol influences energy metabolism in lung ca...
Autores principales: | Lai, Tsung-Ching, Lee, Yueh-Lun, Lee, Wei-Jiunn, Hung, Wen-Yueh, Cheng, Guo-Zhou, Chen, Ji-Qing, Hsiao, Michael, Chien, Ming-Hsien, Chang, Jer-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179427/ https://www.ncbi.nlm.nih.gov/pubmed/35681729 http://dx.doi.org/10.3390/cancers14112750 |
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