Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency

Diseases that affect the mitochondrial electron transport chain (ETC) often manifest as threshold effect disorders, meaning patients only become symptomatic once a certain level of ETC dysfunction is reached. Cells can invoke mechanisms to circumvent reaching their critical ETC threshold, but it is...

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Detalles Bibliográficos
Autores principales: Borror, Megan B., Girotti, Milena, Kar, Adwitiya, Cain, Meghan K., Gao, Xiaoli, MacKay, Vivian L., Herron, Brent, Bhaskaran, Shylesh, Becerra, Sandra, Novy, Nathan, Ventura, Natascia, Johnson, Thomas E., Kennedy, Brian K., Rea, Shane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179431/
https://www.ncbi.nlm.nih.gov/pubmed/35681427
http://dx.doi.org/10.3390/cells11111731

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