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Mutations in KMT2C, BCOR and KDM5C Predict Response to Immune Checkpoint Blockade Therapy in Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Efficient biomarkers are urgently needed to predict response to immune checkpoint blockade (ICB) therapy for non-small cell lung cancer (NSCLC), particularly NSCLC with low tumor mutational burden (TMB). Here, we show that mutations of three chromatin remodeling-related genes, includ...

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Detalles Bibliográficos
Autores principales:	Liu, Dingxie, Benzaquen, Jonathan, Morris, Luc G. T., Ilié, Marius, Hofman, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179442/ https://www.ncbi.nlm.nih.gov/pubmed/35681795 http://dx.doi.org/10.3390/cancers14112816

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