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Combination of OX40 Co-Stimulation, Radiotherapy, and PD-1 Inhibition in a Syngeneic Murine Triple-Negative Breast Cancer Model

SIMPLE SUMMARY: This experimental study was designed in order to investigate the efficacy of the triple combination of radiation (SBRT), PD-1 blockade, and OX40 co-stimulation in a syngeneic murine model using ‘immunologically cold’ triple-negative breast cancer cells. SBRT can induce immunogenic tu...

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Detalles Bibliográficos
Autores principales: Han, Min Guk, Wee, Chan Woo, Kang, Mi Hyun, Kim, Min Ji, Jeon, Seung Hyuck, Kim, In Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179485/
https://www.ncbi.nlm.nih.gov/pubmed/35681672
http://dx.doi.org/10.3390/cancers14112692