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Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients
SIMPLE SUMMARY: Bruton’s tyrosine kinase inhibitor ibrutinib restores T-cell immunity and increases circulating T-cell numbers in chronic lymphocytic leukemia (CLL) patients. Recent evidence suggests T-cell enhanced expansion, rather than increased egress from secondary lymphoid organs (SLO), as a r...
Autores principales: | Mateu-Albero, Tamara, Marcos-Jimenez, Ana, Wissmann, Stefanie, Loscertales, Javier, Terrón, Fernando, Stein, Jens V., Muñoz-Calleja, Cecilia, Cuesta-Mateos, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179528/ https://www.ncbi.nlm.nih.gov/pubmed/35681706 http://dx.doi.org/10.3390/cancers14112729 |
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