Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455

Ionizing radiation activates cytoprotective pathways in cancer cells. Fibroblast growth factor receptor (FGFR) is a key player in these pathways. Thus, FGFR signaling is a potential target to induce radiosensitization. LY2874455 is an orally administrable selective pan-FGFR inhibitor. However, the r...

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Detalles Bibliográficos
Autores principales: Darwis, Narisa Dewi Maulany, Horigome, Eisuke, Li, Shan, Adachi, Akiko, Oike, Takahiro, Shibata, Atsushi, Hirota, Yuka, Ohno, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179643/
https://www.ncbi.nlm.nih.gov/pubmed/35681425
http://dx.doi.org/10.3390/cells11111727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179643/
https://www.ncbi.nlm.nih.gov/pubmed/35681425
http://dx.doi.org/10.3390/cells11111727

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