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Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455

Ionizing radiation activates cytoprotective pathways in cancer cells. Fibroblast growth factor receptor (FGFR) is a key player in these pathways. Thus, FGFR signaling is a potential target to induce radiosensitization. LY2874455 is an orally administrable selective pan-FGFR inhibitor. However, the r...

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Detalles Bibliográficos
Autores principales:	Darwis, Narisa Dewi Maulany, Horigome, Eisuke, Li, Shan, Adachi, Akiko, Oike, Takahiro, Shibata, Atsushi, Hirota, Yuka, Ohno, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179643/ https://www.ncbi.nlm.nih.gov/pubmed/35681425 http://dx.doi.org/10.3390/cells11111727

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