Cargando…
A Multicenter Randomized Phase II Study of Single Agent Efficacy and Optimal Combination Sequence of Everolimus and Pasireotide LAR in Advanced Thyroid Cancer
SIMPLE SUMMARY: Prior clinical studies showed modest activity for single agent everolimus and somatostatin analogues in different subtypes of thyroid cancer; the combination of everolimus and somatostatin analogue was synergistic in preclinical models of thyroid cancer. This randomized trial showed...
Autores principales: | Bauman, Julie E., Chen, Zhengjia, Zhang, Chao, Ohr, James P., Ferris, Robert L., McGorisk, Gerald M., Brandt, Stephen, Srivatsa, Sumathi, Chen, Amy Y., Steuer, Conor E., Shin, Dong M., Saba, Nabil F., Khuri, Fadlo R., Owonikoko, Taofeek K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179856/ https://www.ncbi.nlm.nih.gov/pubmed/35681620 http://dx.doi.org/10.3390/cancers14112639 |
Ejemplares similares
-
Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models
por: Owonikoko, Taofeek K., et al.
Publicado: (2019) -
Interactive Software “Isotonic Design using Normalized Equivalent Toxicity Score (ID-NETS©TM)” for Cancer Phase I Clinical Trials
por: Chen, Zhengjia, et al.
Publicado: (2013) -
Glucose metabolism outcomes in acromegaly patients on treatment with pasireotide-LAR or pasireotide-LAR plus Pegvisomant
por: Chiloiro, Sabrina, et al.
Publicado: (2021) -
Phase 1 safety and pharmacodynamic study of lenalidomide combined with everolimus in patients with advanced solid malignancies with efficacy signal in adenoid cystic carcinoma
por: Harvey, R. Donald, et al.
Publicado: (2020) -
Statistical learning methods as a preprocessing step for survival analysis: evaluation of concept using lung cancer data
por: Behera, Madhusmita, et al.
Publicado: (2011)