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Osteopontin (OPN/SPP1), a Mediator of Tumor Progression, Is Regulated by the Mesenchymal Transcription Factor Slug/SNAI2 in Colorectal Cancer (CRC)

SIMPLE SUMMARY: Expression of the transcription factor Slug/SNAI2 is associated with the epithelial–mesenchymal transition (EMT) and is correlated with poorer disease-free survival in colorectal cancer (CRC). In order to decipher the basis for the Slug-mediated aggressive phenotype, we conducted RNA...

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Detalles Bibliográficos
Autores principales: Amilca-Seba, Katyana, Tan, Tuan Zea, Thiery, Jean-Paul, Louadj, Lila, Thouroude, Sandrine, Bouygues, Anaïs, Sabbah, Michèle, Larsen, Annette K., Denis, Jérôme A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180003/
https://www.ncbi.nlm.nih.gov/pubmed/35681502
http://dx.doi.org/10.3390/cells11111808

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