Cargando…

Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules

Lipoteichoic acid (LTA) is a key cell wall component and virulence factor of Gram-positive bacteria. LTA contributes a major role in infection and it mediates inflammatory responses in the host. Rutaecarpine, an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa, has shown a variety...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jayakumar, Thanasekaran, Yang, Chun-Ming, Yen, Ting-Lin, Hsu, Chia-Yuan, Sheu, Joen-Rong, Hsia, Chih-Wei, Manubolu, Manjunath, Huang, Wei-Chieh, Hsieh, Cheng-Ying, Hsia, Chih-Hsuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180084/ https://www.ncbi.nlm.nih.gov/pubmed/35682568 http://dx.doi.org/10.3390/ijms23115889

Ejemplares similares

Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration
por: Jayakumar, Thanasekaran, et al.
Publicado: (2021)

Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways
por: Hsia, Chih-Hsuan, et al.
Publicado: (2021)

Corrigendum to “Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways”
por: Hsia, Chih-Hsuan, et al.
Publicado: (2022)

Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells
por: Jayakumar, Thanasekaran, et al.
Publicado: (2022)

Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB
por: Huang, Wei-Chieh, et al.
Publicado: (2022)

Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy
por: Jayakumar, Thanasekaran, et al.
Publicado: (2018)

Structure–Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases
por: Yang, Chih-Hao, et al.
Publicado: (2018)

Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on (∙)OH Radicals and HO-1 Expression
por: Jayakumar, Thanasekaran, et al.
Publicado: (2021)

Rutaecarpine, an Alkaloid from Evodia rutaecarpa, Can Prevent Platelet Activation in Humans and Reduce Microvascular Thrombosis in Mice: Crucial Role of the PI3K/Akt/GSK3β Signal Axis through a Cyclic Nucleotides/VASP—Independent Mechanism
por: Huang, Chun-Jen, et al.
Publicado: (2021)

Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling
por: Hsia, Chih-Hsuan, et al.
Publicado: (2018)

Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation
por: Hsia, Chih-Hsuan, et al.
Publicado: (2020)

Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin α(IIb)β(3) inside-out but not outside-in signals
por: Hou, Shaw-Min, et al.
Publicado: (2020)

Mechanisms of glabridin inhibition of integrin α(IIb)β(3) inside-out signals and NF-κB activation in human platelets
por: Huang, Wei-Chieh, et al.
Publicado: (2023)

Myricetin as a promising inhibitor of platelet fibrinogen receptor in humans
por: Chang, Yi, et al.
Publicado: (2023)

Suppression of Human Platelet Activation via Integrin α(IIb)β(3) Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene
por: Hsia, Chih-Wei, et al.
Publicado: (2019)

A Critical Period for the Development of Schizophrenia-Like Pathology by Aberrant Postnatal Neurogenesis
por: Sheu, Joen-Rong, et al.
Publicado: (2019)

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation
por: Shyu, Kou-Gi, et al.
Publicado: (2018)

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation
por: Shyu, Kou-Gi, et al.
Publicado: (2019)

Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice
por: Chung, Chi-Li, et al.
Publicado: (2022)

New Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound
por: Hsia, Chih-Wei, et al.
Publicado: (2017)

Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2–PKC–AKT Activation in Human Platelets
por: Hsia, Chih-Wei, et al.
Publicado: (2019)

Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis
por: Jayakumar, Thanasekaran, et al.
Publicado: (2018)

Antiplatelet Activity of a Newly Synthesized Novel Ruthenium (II): A Potential Role for Akt/JNK Signaling
por: Khamrang, Themmila, et al.
Publicado: (2017)

The uptake of tocopherols by RAW 264.7 macrophages
por: Gao, Rong, et al.
Publicado: (2002)

Ketamine, a Clinically Used Anesthetic, Inhibits Vascular Smooth Muscle Cell Proliferation via PP2A-Activated PI3K/Akt/ERK Inhibition
por: Chang, Yi, et al.
Publicado: (2017)

Novel Therapeutic Agent against Platelet Activation In Vitro and Arterial Thrombosis In Vivo by Morin Hydrate
por: Hsia, Chih-Wei, et al.
Publicado: (2018)

Alkaloids from Tetrastigma hemsleyanum and Their Anti-Inflammatory Effects on LPS-Induced RAW264.7 Cells
por: Wang, Cai Yi, et al.
Publicado: (2018)

Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesis
por: Tseng, Feng-Jen, et al.
Publicado: (2014)

Structure-Antiplatelet Activity Relationships of Novel Ruthenium (II) Complexes: Investigation of Its Molecular Targets
por: Hsia, Chih-Hsuan, et al.
Publicado: (2018)

Factors that Affect the Osteoclastogenesis of RAW264.7 Cells
por: Nguyen, John, et al.
Publicado: (2017)

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies
por: Hsia, Chih-Hsuan, et al.
Publicado: (2017)

Author Correction: A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies
por: Hsia, Chih-Hsuan, et al.
Publicado: (2020)

Three Lipid Emulsions Reduce Staphylococcus aureus-Stimulated Phagocytosis in Mouse RAW264.7 Cells
por: Chen, Ming-Shan, et al.
Publicado: (2021)

Immunomodulatory Effects of N-Acetyl Chitooligosaccharides on RAW264.7 Macrophages
por: Deng, Jun-Jin, et al.
Publicado: (2020)

Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells
por: Youn, Cha Kyung, et al.
Publicado: (2013)

Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells
por: QI, WENTING, et al.
Publicado: (2014)

Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages
por: Liu, Nan, et al.
Publicado: (2014)

Overview of RAW264.7 for osteoclastogensis study: Phenotype and stimuli
por: Kong, Lingbo, et al.
Publicado: (2019)

Immunostimulatory Effect of Laminarin on RAW 264.7 Mouse Macrophages
por: Lee, Ji Young, et al.
Publicado: (2012)

Inductive Effect of Palmatine on Apoptosis in RAW 264.7 Cells
por: Ishikawa, Shintaro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kllc77vehdg134gdngt35ktb05