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Ex Vivo Perfusion Using a Mathematical Modeled, Controlled Gas Exchange Self-Contained Bioreactor Can Maintain a Mouse Kidney for Seven Days
Regenerative medicine requires better pre-clinical tools in order to increase the efficiency of novel therapies transitioning to the clinic. Current monolayer cell culture methods are suboptimal for effectively testing new therapies and live mouse models are expensive, time consuming and require inv...
Autores principales: | Won, Natalie, Castillo-Prado, Jorge, Tan, Xinzhu, Ford, John, Heath, David, Mazilescu, Laura Ioana, Selzner, Markus, Rogers, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180119/ https://www.ncbi.nlm.nih.gov/pubmed/35681517 http://dx.doi.org/10.3390/cells11111822 |
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