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RNA-Seq Profiling of Neutrophil-Derived Microvesicles in Alzheimer’s Disease Patients Identifies a miRNA Signature That May Impact Blood–Brain Barrier Integrity
(1) Background: Systemic infection is associated with increased neuroinflammation and accelerated cognitive decline in AD patients. Activated neutrophils produce neutrophil-derived microvesicles (NMV), which are internalised by human brain microvascular endothelial cells and increase their permeabil...
Autores principales: | Vázquez-Villaseñor, Irina, Smith, Cynthia I., Thang, Yung J. R., Heath, Paul R., Wharton, Stephen B., Blackburn, Daniel J., Ridger, Victoria C., Simpson, Julie E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180128/ https://www.ncbi.nlm.nih.gov/pubmed/35682592 http://dx.doi.org/10.3390/ijms23115913 |
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