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Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis

Background: Excessive accumulation of extracellular matrix is a key feature of pulmonary fibrosis (PF), and myofibroblasts are the main producers of extracellular matrix. Fibroblasts are the major source of myofibroblasts, but the mechanisms of transdifferentiation are unclear. Methods: In vitro, tr...

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Detalles Bibliográficos
Autores principales:	Xu, Xiao, Li, Yiping, Niu, Zhuoya, Xia, Jiarui, Dai, Kai, Wang, Chen, Yao, Wu, Guo, Yonghua, Deng, Xuedan, He, Jing, Deng, Meng, Si, Huifang, Hao, Changfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180362/ https://www.ncbi.nlm.nih.gov/pubmed/35682354 http://dx.doi.org/10.3390/ijerph19116775

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