Oxidative Stress in Malaria: Potential Benefits of Antioxidant Therapy

Malaria is an infectious disease and a serious public health problem in the world, with 3.3 billion people in endemic areas in 100 countries and about 200 million new cases each year, resulting in almost 1 million deaths in 2018. Although studies look for strategies to eradicate malaria, it is neces...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomes, Antonio Rafael Quadros, Cunha, Natasha, Varela, Everton Luiz Pompeu, Brígido, Heliton Patrick Cordovil, Vale, Valdicley Vieira, Dolabela, Maria Fâni, de Carvalho, Eliete Pereira, Percário, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180384/
https://www.ncbi.nlm.nih.gov/pubmed/35682626
http://dx.doi.org/10.3390/ijms23115949
Descripción
Sumario:Malaria is an infectious disease and a serious public health problem in the world, with 3.3 billion people in endemic areas in 100 countries and about 200 million new cases each year, resulting in almost 1 million deaths in 2018. Although studies look for strategies to eradicate malaria, it is necessary to know more about its pathophysiology to understand the underlying mechanisms involved, particularly the redox balance, to guarantee success in combating this disease. In this review, we addressed the involvement of oxidative stress in malaria and the potential benefits of antioxidant supplementation as an adjuvant antimalarial therapy.

Ejemplares similares