Cargando…
A Novel Role of the TRPM4 Ion Channel in Exocytosis
Under physiological conditions, the widely expressed calcium-activated TRPM4 channel conducts sodium into cells. This sodium influx depolarizes the plasma membrane and reduces the driving force for calcium entry. The aberrant expression or function of TRPM4 has been reported in various diseases, inc...
Autores principales: | Stokłosa, Paulina, Kappel, Sven, Peinelt, Christine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180413/ https://www.ncbi.nlm.nih.gov/pubmed/35681487 http://dx.doi.org/10.3390/cells11111793 |
Ejemplares similares
-
TRPM4 in Cancer—A New Potential Drug Target
por: Borgström, Anna, et al.
Publicado: (2021) -
TRP Channels in Digestive Tract Cancers
por: Stokłosa, Paulina, et al.
Publicado: (2020) -
Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells
por: Stokłosa, Paulina, et al.
Publicado: (2021) -
TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells
por: Kappel, Sven, et al.
Publicado: (2019) -
Identification of potent and selective small molecule inhibitors of the cation channel TRPM4
por: Ozhathil, Lijo Cherian, et al.
Publicado: (2018)