Cargando…

Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study

Background—The recent burden of lip and oral cavity, nasopharynx and other pharynx cancer (LOCP) has not been specifically investigated in Europe. Methods—In this descriptive epidemiological study, LOCP was categorised into lip and oral cavity cancer, nasopharynx cancer and other pharynx cancer, wit...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Sullivan, Aisling, Kabir, Zubair, Harding, Máiréad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180496/
https://www.ncbi.nlm.nih.gov/pubmed/35682117
http://dx.doi.org/10.3390/ijerph19116532
_version_ 1784723533226573824
author O’Sullivan, Aisling
Kabir, Zubair
Harding, Máiréad
author_facet O’Sullivan, Aisling
Kabir, Zubair
Harding, Máiréad
author_sort O’Sullivan, Aisling
collection PubMed
description Background—The recent burden of lip and oral cavity, nasopharynx and other pharynx cancer (LOCP) has not been specifically investigated in Europe. Methods—In this descriptive epidemiological study, LOCP was categorised into lip and oral cavity cancer, nasopharynx cancer and other pharynx cancer, with European trends documented using the 2019 Global Burden of Disease (GBD). Summary statistics included deaths, age-standardised incidence rates (ASIR), mortality rates, YLLs (years of life lost), YLDs (years of life lived with disability) and DALYS (disability-adjusted life years). Results—Lip and oral cavity cancer (LO) is the most dominant with the incidence decreasing from 6.2 new cases per 100,000 (95% UI: 6.1–6.4) in 1990 to 5.3 new cases per 100,000 (95% UI: 4.6–6.1). However, nasopharynx cancer (NP) and other pharynx cancer (OP) increased from 1 and 2.2 new cases per 100,000 in 1990 to 1.1 and 3.3 new cases per 100,000 in 2019, respectively. It was noted that LOCP YLLs is much higher than YLDs. In Europe, eastern European countries, specifically Hungary, have the highest burden of LOCP. When LOCP attributable to tobacco in Ireland was compared with the EU, the percentage decrease in OP DALYs attributable to tobacco is below the EU average, whereas the percentage decrease in LO attributable to tobacco in Ireland was above the EU average. Conclusions—There has been a significant increase in ASIR in categories other pharynx and nasopharynx cancer since 1990, with significant geographic variations.
format Online
Article
Text
id pubmed-9180496
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91804962022-06-10 Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study O’Sullivan, Aisling Kabir, Zubair Harding, Máiréad Int J Environ Res Public Health Article Background—The recent burden of lip and oral cavity, nasopharynx and other pharynx cancer (LOCP) has not been specifically investigated in Europe. Methods—In this descriptive epidemiological study, LOCP was categorised into lip and oral cavity cancer, nasopharynx cancer and other pharynx cancer, with European trends documented using the 2019 Global Burden of Disease (GBD). Summary statistics included deaths, age-standardised incidence rates (ASIR), mortality rates, YLLs (years of life lost), YLDs (years of life lived with disability) and DALYS (disability-adjusted life years). Results—Lip and oral cavity cancer (LO) is the most dominant with the incidence decreasing from 6.2 new cases per 100,000 (95% UI: 6.1–6.4) in 1990 to 5.3 new cases per 100,000 (95% UI: 4.6–6.1). However, nasopharynx cancer (NP) and other pharynx cancer (OP) increased from 1 and 2.2 new cases per 100,000 in 1990 to 1.1 and 3.3 new cases per 100,000 in 2019, respectively. It was noted that LOCP YLLs is much higher than YLDs. In Europe, eastern European countries, specifically Hungary, have the highest burden of LOCP. When LOCP attributable to tobacco in Ireland was compared with the EU, the percentage decrease in OP DALYs attributable to tobacco is below the EU average, whereas the percentage decrease in LO attributable to tobacco in Ireland was above the EU average. Conclusions—There has been a significant increase in ASIR in categories other pharynx and nasopharynx cancer since 1990, with significant geographic variations. MDPI 2022-05-27 /pmc/articles/PMC9180496/ /pubmed/35682117 http://dx.doi.org/10.3390/ijerph19116532 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
O’Sullivan, Aisling
Kabir, Zubair
Harding, Máiréad
Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title_full Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title_fullStr Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title_full_unstemmed Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title_short Lip, Oral Cavity and Pharyngeal Cancer Burden in the European Union from 1990–2019 Using the 2019 Global Burden of Disease Study
title_sort lip, oral cavity and pharyngeal cancer burden in the european union from 1990–2019 using the 2019 global burden of disease study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180496/
https://www.ncbi.nlm.nih.gov/pubmed/35682117
http://dx.doi.org/10.3390/ijerph19116532
work_keys_str_mv AT osullivanaisling liporalcavityandpharyngealcancerburdenintheeuropeanunionfrom19902019usingthe2019globalburdenofdiseasestudy
AT kabirzubair liporalcavityandpharyngealcancerburdenintheeuropeanunionfrom19902019usingthe2019globalburdenofdiseasestudy
AT hardingmairead liporalcavityandpharyngealcancerburdenintheeuropeanunionfrom19902019usingthe2019globalburdenofdiseasestudy