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Predicting CRISPR/Cas9 Repair Outcomes by Attention-Based Deep Learning Framework
As a simple and programmable nuclease-based genome editing tool, the CRISPR/Cas9 system has been widely used in target-gene repair and gene-expression regulation. The DNA mutation generated by CRISPR/Cas9-mediated double-strand breaks determines its biological and phenotypic effects. Experiments hav...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180579/ https://www.ncbi.nlm.nih.gov/pubmed/35681543 http://dx.doi.org/10.3390/cells11111847 |