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Predicting CRISPR/Cas9 Repair Outcomes by Attention-Based Deep Learning Framework

As a simple and programmable nuclease-based genome editing tool, the CRISPR/Cas9 system has been widely used in target-gene repair and gene-expression regulation. The DNA mutation generated by CRISPR/Cas9-mediated double-strand breaks determines its biological and phenotypic effects. Experiments hav...

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Detalles Bibliográficos
Autores principales:	Liu, Xiuqin, Wang, Shuya, Ai, Dongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180579/ https://www.ncbi.nlm.nih.gov/pubmed/35681543 http://dx.doi.org/10.3390/cells11111847

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