Gamma Secretase Inhibitors as Potential Therapeutic Targets for Notch Signaling in Uterine Leiomyosarcoma

Uterine leiomyosarcoma (uLMS) is a rare and aggressive cancer with few effective therapeutics. The Notch signaling pathway is evolutionarily conserved with oncogenic properties, but it has not been well studied in uLMS. The purpose of our study was to determine expression of Notch family genes and p...

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Detalles Bibliográficos
Autores principales: Abedin, Yasmin, Gabrilovich, Sofia, Alpert, Emily, Rego, Erica, Begum, Salma, Zhao, Qingshi, Heller, Debra, Einstein, Mark H., Douglas, Nataki C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180633/
https://www.ncbi.nlm.nih.gov/pubmed/35682660
http://dx.doi.org/10.3390/ijms23115980

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