Alveolar Basal Cells Differentiate towards Secretory Epithelial- and Aberrant Basaloid-like Cells In Vitro

In idiopathic pulmonary fibrosis (IPF), keratin (KRT)17+/KRT5+ basal and KRT17+/KRT5− aberrant basaloid cells are atypically present within the alveolar space. We previously described the fibrosis-enriched outgrowth of alveolar basal cells from peripheral fibrotic lung tissue. Using single cell RNA...

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Detalles Bibliográficos
Autores principales: Khan, Petra, Roux, Julien, Blumer, Sabrina, Knudsen, Lars, Jonigk, Danny, Kuehnel, Mark P., Tamm, Michael, Hostettler, Katrin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180703/
https://www.ncbi.nlm.nih.gov/pubmed/35681516
http://dx.doi.org/10.3390/cells11111820

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