Substituted Syndecan-2-Derived Mimetic Peptides Show Improved Antitumor Activity over the Parent Syndecan-2-Derived Peptide

We previously showed that a synthetic peptide (S2-P) corresponding to a portion of the human syndecan-2 (SDC2) sequence can bind to the pro-domain of matrix metalloproteinase-7 (MMP-7) to inhibit colon cancer activities. Since S2-P had a relatively weak binding affinity for the MMP-7 pro-domain, we...

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Detalles Bibliográficos
Autores principales: Jang, Bohee, Kim, Ayoung, Lee, Yejin, Hwang, Jisun, Sung, Jee-Young, Jang, Eun-Ju, Kim, Yong-Nyun, Yun, Ji-Hye, Han, Jeongmin, Song, Ji-Joon, Lee, Weontae, Oh, Eok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180903/
https://www.ncbi.nlm.nih.gov/pubmed/35682569
http://dx.doi.org/10.3390/ijms23115888

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