Cargando…

Beyond Genetics: Metastasis as an Adaptive Response in Breast Cancer

Metastatic disease represents the primary cause of breast cancer (BC) mortality, yet it is still one of the most enigmatic processes in the biology of this tumor. Metastatic progression includes distinct phases: invasion, intravasation, hematogenous dissemination, extravasation and seeding at distan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruscitto, Federica, Roda, Niccolò, Priami, Chiara, Migliaccio, Enrica, Pelicci, Pier Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181003/ https://www.ncbi.nlm.nih.gov/pubmed/35682953 http://dx.doi.org/10.3390/ijms23116271

Ejemplares similares

p53 and aging: role of p66Shc
por: Migliaccio, Enrica, et al.
Publicado: (2013)

Blood Vessels and Peripheral Nerves as Key Players in Cancer Progression and Therapy Resistance
por: Roda, Niccolò, et al.
Publicado: (2021)

P66SHC deletion improves fertility and progeric phenotype of late‐generation TERC‐deficient mice but not their short lifespan
por: Giorgio, Marco, et al.
Publicado: (2016)

On the epigenetic role of guanosine oxidation
por: Giorgio, Marco, et al.
Publicado: (2019)

P66Shc signals to age
por: Trinei, Mirella, et al.
Publicado: (2009)

WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
por: Punzi, Simona, et al.
Publicado: (2019)

Erratum. Deletion of p66(Shc) Longevity Gene Protects Against Experimental Diabetic Glomerulopathy by Preventing Diabetes-Induced Oxidative Stress. Diabetes 2006;55:1642–1650
por: Menini, Stefano, et al.
Publicado: (2018)

Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging
por: Gambino, Valentina, et al.
Publicado: (2013)

From Double-Strand Break Recognition to Cell-Cycle Checkpoint Activation: High Content and Resolution Image Cytometry Unmasks 53BP1 Multiple Roles in DNA Damage Response and p53 Action
por: Furia, Laura, et al.
Publicado: (2022)

Metabolic Constrains Rule Metastasis Progression
por: Roda, Niccolo’, et al.
Publicado: (2020)

Heating cancer stem cells to reduce tumor relapse
por: Pelicci, Pier Giuseppe, et al.
Publicado: (2011)

Automated multimodal fluorescence microscopy for hyperplex spatial-proteomics: Coupling microfluidic-based immunofluorescence to high resolution, high sensitivity, three-dimensional analysis of histological slides
por: Furia, Laura, et al.
Publicado: (2022)

Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities
por: Caprioli, Chiara, et al.
Publicado: (2022)

Corrigendum: Single-cell technologies to decipher the immune microenvironment in myeloid neoplasms: Perspectives and opportunities
por: Caprioli, Chiara, et al.
Publicado: (2022)

Correlative Multi-Modal Microscopy: A Novel Pipeline for Optimizing Fluorescence Microscopy Resolutions in Biological Applications
por: Pelicci, Simone, et al.
Publicado: (2023)

Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer
por: Bonetti, Paola, et al.
Publicado: (2018)

Correction: Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer
por: Bonetti, Paola, et al.
Publicado: (2019)

Introducing Infectious Agents and Cancer
por: Buonaguro, Franco M, et al.
Publicado: (2006)

The Oxidative Stress Response Gene P66 and the Tumor Suppressor Gene P53 Induce Mitochondrial Dna Damages
por: Trinei, Mirella, et al.
Publicado: (2001)

Is PML a Tumor Suppressor?
por: Mazza, Massimiliano, et al.
Publicado: (2013)

Beyond collective intelligence: Collective adaptation
por: Galesic, Mirta, et al.
Publicado: (2023)

Chemotherapy-Exacerbated Breast Cancer Metastasis: A Paradox Explainable by Dysregulated Adaptive-Response
por: Middleton, Justin D., et al.
Publicado: (2018)

Regulatory Crosstalk of Doxorubicin, Estradiol and TNFα Combined Treatment in Breast Cancer-derived Cell Lines
por: Nassiri, Isar, et al.
Publicado: (2019)

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data
por: Melloni, Giorgio E. M., et al.
Publicado: (2017)

Awaking stem cells from dormancy: growing old and fighting cancer
por: Viale, Andrea, et al.
Publicado: (2009)

Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs
por: Punzi, Simona, et al.
Publicado: (2019)

Molecular biology of breast cancer metastasis: Genetic regulation of human breast carcinoma metastasis
por: Welch, Danny R, et al.
Publicado: (2000)

Novel Tools to Measure Single Molecules Colocalization in Fluorescence Nanoscopy by Image Cross Correlation Spectroscopy
por: Pelicci, Simone, et al.
Publicado: (2022)

Epithelial plasticity in cancer: beyond metastasis
por: Thomson, Timothy M., et al.
Publicado: (2018)

Genomics of Acute Myeloid Leukemia: The Next Generation
por: Riva, Laura, et al.
Publicado: (2012)

The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration
por: Savino, Costanza, et al.
Publicado: (2013)

Cerebro: interactive visualization of scRNA-seq data
por: Hillje, Roman, et al.
Publicado: (2020)

Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process
por: Melixetian, Marine, et al.
Publicado: (2022)

Breast Cancer with Brain Metastasis: Molecular Insights and Clinical Management
por: Ivanova, Mariia, et al.
Publicado: (2023)

Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications
por: Hadjipanteli, Andria, et al.
Publicado: (2020)

An intrabody specific for the nucleophosmin carboxy-terminal mutant and fused to a nuclear localization sequence binds its antigen but fails to relocate it in the nucleus
por: Martinelli, Chiara, et al.
Publicado: (2014)

Tumor mutational burden quantification from targeted gene panels: major advancements and challenges
por: Fancello, Laura, et al.
Publicado: (2019)

Human cord blood (hCB)-CD34(+) humanized mice fail to reject human acute myeloid leukemia cells
por: Tanaskovic, Olga, et al.
Publicado: (2019)

Semantic and Geographical Analysis of COVID-19 Trials Reveals a Fragmented Clinical Research Landscape Likely to Impair Informativeness
por: Tini, Giulia, et al.
Publicado: (2020)

RNAi screens identify CHD4 as an essential gene in breast cancer growth
por: D'Alesio, Carolina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mqvaopskt88h3tu5kpr14sfhh4