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Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA

AppA, the Escherichia coli periplasmic phytase of clade 2 of the histidine phosphatase (HP2) family, has been well-characterized and successfully engineered for use as an animal feed supplement. AppA is a 1D-6-phytase and highly stereospecific but transiently accumulates 1D-myo-Ins(2,3,4,5)P(4) and...

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Detalles Bibliográficos
Autores principales:	Acquistapace, Isabella M., Thompson, Emma J., Kühn, Imke, Bedford, Mike R., Brearley, Charles A., Hemmings, Andrew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181005/ https://www.ncbi.nlm.nih.gov/pubmed/35683026 http://dx.doi.org/10.3390/ijms23116346

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