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Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses

We report robust SARS-CoV2 neutralizing sdAbs targeting the viral peptides encompassing the polybasic cleavage site (CSP) and in the receptor binding domain (RBD) of the spike (S) protein. Both the sdAbs inhibited infectivity of the CoV2 S protein expressing pseudoviruses (LV-CoV2S). Both anti-CSP a...

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Detalles Bibliográficos
Autores principales:	Singh, Sudhakar, Dahiya, Surbhi, Singh, Yuviana J., Beeton, Komal, Jain, Ayush, Sarkar, Roman, Dubey, Abhishek, Tehseen, Azeez, Sehrawat, Sharvan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181070/ https://www.ncbi.nlm.nih.gov/pubmed/35702569 http://dx.doi.org/10.1016/j.isci.2022.104549

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