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Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair

Complex rotator cuff tears provide a significant challenge for treating surgeons, given their high failure rate following repair and the associated morbidity. The purpose of this study is to evaluate the clinical outcomes of patients who underwent biologically enhanced demineralized bone matrix augm...

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Autores principales: Wellington, Ian J., Muench, Lukas N., Hawthorne, Benjamin C., Uyeki, Colin L., Antonacci, Christopher L., McCarthy, Mary Beth, Connors, John P., Kia, Cameron, Mazzocca, Augustus D., Berthold, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181072/
https://www.ncbi.nlm.nih.gov/pubmed/35683345
http://dx.doi.org/10.3390/jcm11112956
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author Wellington, Ian J.
Muench, Lukas N.
Hawthorne, Benjamin C.
Uyeki, Colin L.
Antonacci, Christopher L.
McCarthy, Mary Beth
Connors, John P.
Kia, Cameron
Mazzocca, Augustus D.
Berthold, Daniel P.
author_facet Wellington, Ian J.
Muench, Lukas N.
Hawthorne, Benjamin C.
Uyeki, Colin L.
Antonacci, Christopher L.
McCarthy, Mary Beth
Connors, John P.
Kia, Cameron
Mazzocca, Augustus D.
Berthold, Daniel P.
author_sort Wellington, Ian J.
collection PubMed
description Complex rotator cuff tears provide a significant challenge for treating surgeons, given their high failure rate following repair and the associated morbidity. The purpose of this study is to evaluate the clinical outcomes of patients who underwent biologically enhanced demineralized bone matrix augmentation of rotator cuff repairs. Twenty patients with complex rotator cuff tears underwent arthroscopic rotator cuff repair by a single surgeon with demineralized bone matrix (DBM) augmentation that was biologically enhanced with platelet-rich plasma and concentrated bone marrow aspirate. Post-operative MRI was used to determine surgical success. Patient reported outcome measures and range of motion data were collected pre-operatively and at the final post-operative visit for each patient. Ten patients (50%) with DBM augmentation of their arthroscopic rotator cuff repair were deemed non-failures. The failure group had less improvement of visual analogue pain scale (p = 0.017), Simple Shoulder Test (p = 0.032), Single Assessment Numerical Evaluation (p = 0.006) and abduction (p = 0.046). There was no difference between the groups for change in American Shoulder and Elbow Society score (p = 0.096), Constant-Murley score (p = 0.086), forward elevation (p = 0.191) or external rotation (p = 0.333). The present study found that 50% of patients who underwent biologically enhanced DBM augmentation of their rotator cuff repair demonstrated MRI-determined failure of supraspinatus healing.
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spelling pubmed-91810722022-06-10 Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair Wellington, Ian J. Muench, Lukas N. Hawthorne, Benjamin C. Uyeki, Colin L. Antonacci, Christopher L. McCarthy, Mary Beth Connors, John P. Kia, Cameron Mazzocca, Augustus D. Berthold, Daniel P. J Clin Med Article Complex rotator cuff tears provide a significant challenge for treating surgeons, given their high failure rate following repair and the associated morbidity. The purpose of this study is to evaluate the clinical outcomes of patients who underwent biologically enhanced demineralized bone matrix augmentation of rotator cuff repairs. Twenty patients with complex rotator cuff tears underwent arthroscopic rotator cuff repair by a single surgeon with demineralized bone matrix (DBM) augmentation that was biologically enhanced with platelet-rich plasma and concentrated bone marrow aspirate. Post-operative MRI was used to determine surgical success. Patient reported outcome measures and range of motion data were collected pre-operatively and at the final post-operative visit for each patient. Ten patients (50%) with DBM augmentation of their arthroscopic rotator cuff repair were deemed non-failures. The failure group had less improvement of visual analogue pain scale (p = 0.017), Simple Shoulder Test (p = 0.032), Single Assessment Numerical Evaluation (p = 0.006) and abduction (p = 0.046). There was no difference between the groups for change in American Shoulder and Elbow Society score (p = 0.096), Constant-Murley score (p = 0.086), forward elevation (p = 0.191) or external rotation (p = 0.333). The present study found that 50% of patients who underwent biologically enhanced DBM augmentation of their rotator cuff repair demonstrated MRI-determined failure of supraspinatus healing. MDPI 2022-05-24 /pmc/articles/PMC9181072/ /pubmed/35683345 http://dx.doi.org/10.3390/jcm11112956 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wellington, Ian J.
Muench, Lukas N.
Hawthorne, Benjamin C.
Uyeki, Colin L.
Antonacci, Christopher L.
McCarthy, Mary Beth
Connors, John P.
Kia, Cameron
Mazzocca, Augustus D.
Berthold, Daniel P.
Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title_full Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title_fullStr Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title_full_unstemmed Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title_short Clinical Outcomes following Biologically Enhanced Demineralized Bone Matrix Augmentation of Complex Rotator Cuff Repair
title_sort clinical outcomes following biologically enhanced demineralized bone matrix augmentation of complex rotator cuff repair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181072/
https://www.ncbi.nlm.nih.gov/pubmed/35683345
http://dx.doi.org/10.3390/jcm11112956
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