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Antiproliferative Effects of the Aptamer d(GGGT)(4) and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells

In this paper, we study the T30923 antiproliferative potential and the contribution of its loop residues in six different human cancer cell lines by preparing five T30923 variants using the single residue replacement approach of loop thymidine with an abasic site mimic (S). G-rich oligonucleotides (...

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Detalles Bibliográficos
Autores principales: Virgilio, Antonella, Pecoraro, Annalisa, Benigno, Daniela, Russo, Annapina, Russo, Giulia, Esposito, Veronica, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181107/
https://www.ncbi.nlm.nih.gov/pubmed/35682635
http://dx.doi.org/10.3390/ijms23115952