NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides

In inflammatory bone diseases such as periodontitis, the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing 3 (NLRP3) inflammasome accelerates bone resorption by promoting proinflammatory cytokine IL-1β production. However, the role of the NLRP3 inflammasome...

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Detalles Bibliográficos
Autores principales: Alam, Mohammad Ibtehaz, Mae, Megumi, Farhana, Fatima, Oohira, Masayuki, Yamashita, Yasunori, Ozaki, Yukio, Sakai, Eiko, Yoshimura, Atsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181162/
https://www.ncbi.nlm.nih.gov/pubmed/35682777
http://dx.doi.org/10.3390/ijms23116096

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