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Enhanced Extracellular Transfer of HLA-DQ Activates CD3(+) Lymphocytes towards Compromised Treg Induction in Celiac Disease

Celiac disease (CeD) manifests with autoimmune intestinal inflammation from gluten and genetic predisposition linked to human leukocyte antigen class-II (HLA-II) gene variants. Antigen-presenting cells facilitate gluten exposition through the interaction of their surface major histocompatibility com...

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Detalles Bibliográficos
Autores principales: Hudec, Michael, Juříčková, Iva, Riegerová, Kamila, Ovsepian, Saak V., Černá, Marie, O’Leary, Valerie Bríd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181181/
https://www.ncbi.nlm.nih.gov/pubmed/35682780
http://dx.doi.org/10.3390/ijms23116102