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Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold
Malignant Pleural Mesothelioma (MPM) is a highly aggressive disease whose diagnosis could be challenging and confusing. It could occur with atypical presentations on every examined level. Here, we present three unconventional cases of the complex diagnostic process of MPM that we have experienced du...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181256/ https://www.ncbi.nlm.nih.gov/pubmed/35683612 http://dx.doi.org/10.3390/jcm11113225 |
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author | Orlandi, Riccardo Bono, Francesca Cortinovis, Diego Luigi Cardillo, Giuseppe Cioffi, Ugo Guttadauro, Angelo Pirondini, Emanuele Canova, Stefania Cassina, Enrico Mario Raveglia, Federico |
author_facet | Orlandi, Riccardo Bono, Francesca Cortinovis, Diego Luigi Cardillo, Giuseppe Cioffi, Ugo Guttadauro, Angelo Pirondini, Emanuele Canova, Stefania Cassina, Enrico Mario Raveglia, Federico |
author_sort | Orlandi, Riccardo |
collection | PubMed |
description | Malignant Pleural Mesothelioma (MPM) is a highly aggressive disease whose diagnosis could be challenging and confusing. It could occur with atypical presentations on every examined level. Here, we present three unconventional cases of the complex diagnostic process of MPM that we have experienced during routine practice: a patient with reactive mesothelial hyperplasia mimicking MPM, an unexpected presentation of MPM with persistent unilateral hydropneumothorax, a rare case of MPM in situ. Then, we review the relevant literature on each of these topics. Definitive biomarkers to confidently distinguish MPM from other pleural affections are still demanded. Patients presenting with persistent hydropneumothorax must always be investigated for MPM. MPM in situ is now a reality, and this raises questions about its management. |
format | Online Article Text |
id | pubmed-9181256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91812562022-06-10 Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold Orlandi, Riccardo Bono, Francesca Cortinovis, Diego Luigi Cardillo, Giuseppe Cioffi, Ugo Guttadauro, Angelo Pirondini, Emanuele Canova, Stefania Cassina, Enrico Mario Raveglia, Federico J Clin Med Article Malignant Pleural Mesothelioma (MPM) is a highly aggressive disease whose diagnosis could be challenging and confusing. It could occur with atypical presentations on every examined level. Here, we present three unconventional cases of the complex diagnostic process of MPM that we have experienced during routine practice: a patient with reactive mesothelial hyperplasia mimicking MPM, an unexpected presentation of MPM with persistent unilateral hydropneumothorax, a rare case of MPM in situ. Then, we review the relevant literature on each of these topics. Definitive biomarkers to confidently distinguish MPM from other pleural affections are still demanded. Patients presenting with persistent hydropneumothorax must always be investigated for MPM. MPM in situ is now a reality, and this raises questions about its management. MDPI 2022-06-06 /pmc/articles/PMC9181256/ /pubmed/35683612 http://dx.doi.org/10.3390/jcm11113225 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Orlandi, Riccardo Bono, Francesca Cortinovis, Diego Luigi Cardillo, Giuseppe Cioffi, Ugo Guttadauro, Angelo Pirondini, Emanuele Canova, Stefania Cassina, Enrico Mario Raveglia, Federico Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title | Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title_full | Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title_fullStr | Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title_full_unstemmed | Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title_short | Sneaky Diagnosis of Pleural Malignant Mesothelioma in Thoracic Surgery: All That Glitters Is Not Gold |
title_sort | sneaky diagnosis of pleural malignant mesothelioma in thoracic surgery: all that glitters is not gold |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181256/ https://www.ncbi.nlm.nih.gov/pubmed/35683612 http://dx.doi.org/10.3390/jcm11113225 |
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