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Genetic Evidence for a Causal Relationship between Hyperlipidemia and Type 2 Diabetes in Mice

Dyslipidemia is considered a risk factor for type 2 diabetes (T2D), yet studies with statins and candidate genes suggest that circulating lipids may protect against T2D development. Apoe-null (Apoe(-/-)) mouse strains develop spontaneous dyslipidemia and exhibit a wide variation in susceptibility to...

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Detalles Bibliográficos
Autores principales: Shi, Lisa J., Tang, Xiwei, He, Jiang, Shi, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181284/
https://www.ncbi.nlm.nih.gov/pubmed/35682864
http://dx.doi.org/10.3390/ijms23116184