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Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1

Specialized pro-resolving mediators (SPMs), including Maresins (MaR)-1 and 2, contribute to tear film homeostasis and resolve conjunctival inflammation. We investigated MaR2′s signaling pathways in goblet cells (GC) from rat conjunctiva. Agonist-induced [Ca(2+)](i) and high-molecular weight glycocon...

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Detalles Bibliográficos
Autores principales: Olsen, Markus V., Lyngstadaas, Anne V., Bair, Jeffrey A., Hodges, Robin R., Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181304/
https://www.ncbi.nlm.nih.gov/pubmed/35682912
http://dx.doi.org/10.3390/ijms23116233