Oncostatin M Counteracts the Fibrotic Effects of TGF-β1 and IL-4 on Nasal-Polyp-Derived Fibroblasts: A Control of Fibrosis in Chronic Rhinosinusitis with Nasal Polyps?

Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with inflammation and tissue remodeling including myofibroblasts differentiation and extracellular matrix (ECM) deposition mediated by TGF-β1 and IL-4. Oncostatin M (OSM) is a cytokine involved in fibrotic processes in other cellular su...

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Detalles Bibliográficos
Autores principales: Carsuzaa, Florent, Béquignon, Émilie, Bainaud, Matthieu, Jégou, Jean-François, Dufour, Xavier, Lecron, Jean-Claude, Favot, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181333/
https://www.ncbi.nlm.nih.gov/pubmed/35682987
http://dx.doi.org/10.3390/ijms23116308

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