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A Micro-Immunotherapy Sequential Medicine MIM-seq Displays Immunomodulatory Effects on Human Macrophages and Anti-Tumor Properties towards In Vitro 2D and 3D Models of Colon Carcinoma and in an In Vivo Subcutaneous Xenograft Colon Carcinoma Model
In this study, the immunomodulatory effects of a sequential micro-immunotherapy medicine, referred as MIM-seq, were appraised in human primary M1 and M2 macrophages, in which the secretion of pro-inflammatory cytokines, such as interleukin (IL)-1β, IL-6, IL-12, IL-23, and tumor necrosis factor (TNF)...
Autores principales: | Jacques, Camille, Marchesi, Irene, Fiorentino, Francesco Paolo, Chatelais, Mathias, Lilli, Nicoletta Libera, Appel, Kurt, Lejeune, Beatrice, Floris, Ilaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181410/ https://www.ncbi.nlm.nih.gov/pubmed/35682738 http://dx.doi.org/10.3390/ijms23116059 |
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