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Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD

Maternal obesity and consumption of a high-fat diet significantly elevate risk for pediatric nonalcoholic fatty liver disease (NAFLD), affecting 10% of children in the US. Almost half of these children are diagnosed with nonalcoholic steatohepatitis (NASH), a leading etiology for liver transplant. A...

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Detalles Bibliográficos
Autores principales: Mandala, Ashok, Dobrinskikh, Evgenia, Janssen, Rachel C., Fiehn, Oliver, D’Alessandro, Angelo, Friedman, Jacob E., Jonscher, Karen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181499/
https://www.ncbi.nlm.nih.gov/pubmed/35682720
http://dx.doi.org/10.3390/ijms23116043