Cargando…

Effects of Axonal Demyelination, Inflammatory Cytokines and Divalent Cation Chelators on Thalamic HCN Channels and Oscillatory Bursting

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is characterized by the progressive loss of oligodendrocytes and myelin and is associated with thalamic dysfunction. Cuprizone (CPZ)-induced general demyelination in rodents is a valuable model for studying differe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oniani, Tengiz, Vinnenberg, Laura, Chaudhary, Rahul, Schreiber, Julian A., Riske, Kathrin, Williams, Brandon, Pape, Hans-Christian, White, John A., Junker, Anna, Seebohm, Guiscard, Meuth, Sven G., Hundehege, Petra, Budde, Thomas, Zobeiri, Mehrnoush
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181513/ https://www.ncbi.nlm.nih.gov/pubmed/35682964 http://dx.doi.org/10.3390/ijms23116285

Ejemplares similares

The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System
por: Zobeiri, Mehrnoush, et al.
Publicado: (2019)

Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels
por: Zobeiri, Mehrnoush, et al.
Publicado: (2017)

Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system
por: Peischard, Stefan, et al.
Publicado: (2022)

Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines
por: Chaudhary, Rahul, et al.
Publicado: (2022)

Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides
por: Datunashvili, Maia, et al.
Publicado: (2018)

An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities
por: Wemhöner, Konstantin, et al.
Publicado: (2015)

Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals
por: Wall, Richard J., et al.
Publicado: (2018)

Synthesis of Ionizable Calix[4]arenes for Chelation of Selected Divalent Cations
por: Blumberg, Markus, et al.
Publicado: (2022)

Paving the Way to Understand Autoantibody-Mediated Epilepsy on the Molecular Level
por: Seebohm, Guiscard, et al.
Publicado: (2015)

The Brain Network in a Model of Thalamocortical Dysrhythmia
por: Zobeiri, Mehrnoush, et al.
Publicado: (2019)

Ischemia-induced cell depolarization: does the hyperpolarization-activated cation channel HCN2 affect the outcome after stroke in mice?
por: Ehling, Petra, et al.
Publicado: (2013)

Klotho: A new trafficking modifier of Kv7.1/KCNE1 channels
por: Strutz-Seebohm, Nathalie, et al.
Publicado: (2014)

Salts of HCN‐Cyanide Aggregates: [CN(HCN)(2)](−) and [CN(HCN)(3)](−)
por: Bläsing, Kevin, et al.
Publicado: (2020)

The KCNE Tango – How KCNE1 Interacts with Kv7.1
por: Wrobel, Eva, et al.
Publicado: (2012)

A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors
por: Schreiber, Julian A., et al.
Publicado: (2019)

From iPSC towards cardiac tissue—a road under construction
por: Peischard, Stefan, et al.
Publicado: (2017)

Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes
por: Ritter, Nadine, et al.
Publicado: (2023)

Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation
por: Zhang, Shaoping, et al.
Publicado: (2014)

The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells
por: Jen, Huan-I, et al.
Publicado: (2020)

Thalamocortical-auditory network alterations following cuprizone‐induced demyelination
por: Ghaffarian, Nikoo, et al.
Publicado: (2016)

Myocardial Damage by SARS-CoV-2: Emerging Mechanisms and Therapies
por: Ho, Huyen Tran, et al.
Publicado: (2021)

Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter
por: Schreiber, Julian Alexander, et al.
Publicado: (2023)

Human pluripotent stem cell-derived cardiomyocytes: Genome-wide expression profiling of long-term in vitro maturation in comparison to human heart tissue
por: Piccini, Ilaria, et al.
Publicado: (2015)

In Vitro Model Systems of Coxsackievirus B3-Induced Myocarditis: Comparison of Commonly Used Cell Lines and Characterization of CVB3-Infected iCell(®) Cardiomyocytes
por: Kraft, Lisa, et al.
Publicado: (2021)

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis
por: Amedonu, Elsie, et al.
Publicado: (2019)

Functional high-resolution time-course expression analysis of human embryonic stem cells undergoing cardiac induction
por: Piccini, Ilaria, et al.
Publicado: (2016)

K(Ca) channel blockers increase effectiveness of the EGF receptor TK inhibitor erlotinib in non-small cell lung cancer cells (A549)
por: Glaser, Felix, et al.
Publicado: (2021)

Functional MRI reveals brain-wide actions of thalamically-initiated oscillatory activities on associative memory consolidation
por: Wang, Xunda, et al.
Publicado: (2023)

NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes
por: Matschke, Veronika, et al.
Publicado: (2015)

Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats
por: Zhang, Lin, et al.
Publicado: (2013)

Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives
por: Ritter, Nadine, et al.
Publicado: (2023)

Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination
por: Kapell, Hannah, et al.
Publicado: (2023)

Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination
por: Cerina, Manuela, et al.
Publicado: (2018)

Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca(2+ )permeability and Mg(2+ )block
por: Cavara, Nora A, et al.
Publicado: (2010)

The Linker Pivot in Ci-VSP: The Key to Unlock Catalysis
por: Hobiger, Kirstin, et al.
Publicado: (2013)

Thalamic Bursts and the Epic Pain Model
por: Saab, Carl Y., et al.
Publicado: (2017)

HCN Channels and Heart Rate
por: Scicchitano, Pietro, et al.
Publicado: (2012)

Review: HCN Channels in the Heart
por: Depuydt, Anne-Sophie, et al.
Publicado: (2022)

Selective optical drive of thalamic reticular nucleus generates thalamic bursts & cortical spindles
por: Halassa, Michael M., et al.
Publicado: (2011)

Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formation
por: Disse, Paul, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tq86ilqpap81d7h3lbiqrr4569