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Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes
Acrylamide (AA) toxicity is associated with oxidative stress. During detoxification, AA is either coupled to gluthatione or biotransformed to glycidamide by the enzyme cytochrome P450 2E1 (CYP2E1). The aim of our study was to examine the hepatotoxicity of AA in vivo and in vitro. Thirty male Wistar...
Autores principales: | Marković Filipović, Jelena, Miler, Marko, Kojić, Danijela, Karan, Jelena, Ivelja, Ivana, Čukuranović Kokoris, Jovana, Matavulj, Milica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181519/ https://www.ncbi.nlm.nih.gov/pubmed/35682741 http://dx.doi.org/10.3390/ijms23116062 |
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