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New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis

(1) Background: New pulse modulation (PM) technologies in Holmium:YAG lasers are available for urinary stone treatment, but little is known about them. We aim to systematically evaluate the published evidence in terms of their lithotripsy performance. (2) Methods: A systematic electronic search was...

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Autores principales: Sánchez-Puy, Antoni, Bravo-Balado, Alejandra, Diana, Pietro, Baboudjian, Michael, Piana, Alberto, Girón, Irene, Kanashiro, Andrés K., Angerri, Oriol, Contreras, Pablo, Eisner, Brian H., Balañà, Josep, Sánchez-Martín, Francisco M., Millán, Félix, Palou, Joan, Emiliani, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181640/
https://www.ncbi.nlm.nih.gov/pubmed/35683595
http://dx.doi.org/10.3390/jcm11113208
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author Sánchez-Puy, Antoni
Bravo-Balado, Alejandra
Diana, Pietro
Baboudjian, Michael
Piana, Alberto
Girón, Irene
Kanashiro, Andrés K.
Angerri, Oriol
Contreras, Pablo
Eisner, Brian H.
Balañà, Josep
Sánchez-Martín, Francisco M.
Millán, Félix
Palou, Joan
Emiliani, Esteban
author_facet Sánchez-Puy, Antoni
Bravo-Balado, Alejandra
Diana, Pietro
Baboudjian, Michael
Piana, Alberto
Girón, Irene
Kanashiro, Andrés K.
Angerri, Oriol
Contreras, Pablo
Eisner, Brian H.
Balañà, Josep
Sánchez-Martín, Francisco M.
Millán, Félix
Palou, Joan
Emiliani, Esteban
author_sort Sánchez-Puy, Antoni
collection PubMed
description (1) Background: New pulse modulation (PM) technologies in Holmium:YAG lasers are available for urinary stone treatment, but little is known about them. We aim to systematically evaluate the published evidence in terms of their lithotripsy performance. (2) Methods: A systematic electronic search was performed (MEDLINE, Scopus, and Cochrane databases). We included all relevant publications, including randomized controlled trials, non-randomized comparative and non-comparative studies, and in-vitro studies investigating Holmium:YAG lithotripsy performance employing any new PM. (3) Results: Initial search yielded 203 studies; 24 studies were included after selection: 15 in-vitro, 9 in-vivo. 10 In-vitro compared Moses with regular PM, 1 compared Quanta’s, 1 Dornier MedTech’s, 2 Moses with super Thulium Fiber Laser, and 1 compared Moses with Quanta PMs. Six out of seven comparative studies found a statistically significant difference in favor of new-generation PM technologies in terms of operative time and five out of six in fragmentation time; two studies evaluated retropulsion, both in favor of new-generation PM. There were no statistically significant differences regarding stone-free rate, lasing and operative time, and complications between Moses and regular PM when data were meta-analyzed. (4) Conclusions: Moses PM seems to have better lithotripsy performance than regular modes in in-vitro studies, but there are still some doubts about its in-vivo results. Little is known about the other PMs. Although some results favor Quanta PMs, further studies are needed.
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spelling pubmed-91816402022-06-10 New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis Sánchez-Puy, Antoni Bravo-Balado, Alejandra Diana, Pietro Baboudjian, Michael Piana, Alberto Girón, Irene Kanashiro, Andrés K. Angerri, Oriol Contreras, Pablo Eisner, Brian H. Balañà, Josep Sánchez-Martín, Francisco M. Millán, Félix Palou, Joan Emiliani, Esteban J Clin Med Systematic Review (1) Background: New pulse modulation (PM) technologies in Holmium:YAG lasers are available for urinary stone treatment, but little is known about them. We aim to systematically evaluate the published evidence in terms of their lithotripsy performance. (2) Methods: A systematic electronic search was performed (MEDLINE, Scopus, and Cochrane databases). We included all relevant publications, including randomized controlled trials, non-randomized comparative and non-comparative studies, and in-vitro studies investigating Holmium:YAG lithotripsy performance employing any new PM. (3) Results: Initial search yielded 203 studies; 24 studies were included after selection: 15 in-vitro, 9 in-vivo. 10 In-vitro compared Moses with regular PM, 1 compared Quanta’s, 1 Dornier MedTech’s, 2 Moses with super Thulium Fiber Laser, and 1 compared Moses with Quanta PMs. Six out of seven comparative studies found a statistically significant difference in favor of new-generation PM technologies in terms of operative time and five out of six in fragmentation time; two studies evaluated retropulsion, both in favor of new-generation PM. There were no statistically significant differences regarding stone-free rate, lasing and operative time, and complications between Moses and regular PM when data were meta-analyzed. (4) Conclusions: Moses PM seems to have better lithotripsy performance than regular modes in in-vitro studies, but there are still some doubts about its in-vivo results. Little is known about the other PMs. Although some results favor Quanta PMs, further studies are needed. MDPI 2022-06-04 /pmc/articles/PMC9181640/ /pubmed/35683595 http://dx.doi.org/10.3390/jcm11113208 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Sánchez-Puy, Antoni
Bravo-Balado, Alejandra
Diana, Pietro
Baboudjian, Michael
Piana, Alberto
Girón, Irene
Kanashiro, Andrés K.
Angerri, Oriol
Contreras, Pablo
Eisner, Brian H.
Balañà, Josep
Sánchez-Martín, Francisco M.
Millán, Félix
Palou, Joan
Emiliani, Esteban
New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title_full New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title_fullStr New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title_full_unstemmed New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title_short New Generation Pulse Modulation in Holmium:YAG Lasers: A Systematic Review of the Literature and Meta-Analysis
title_sort new generation pulse modulation in holmium:yag lasers: a systematic review of the literature and meta-analysis
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181640/
https://www.ncbi.nlm.nih.gov/pubmed/35683595
http://dx.doi.org/10.3390/jcm11113208
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