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Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are characterized by the aberrant accumulation of intracytoplasmic misfolded and aggregated α-synuclein (α-Syn), resulting in neurodegeneration associated with inflammation. The propagation of α-Syn aggregates from cell to cell is implicat...
Autores principales: | Zagorski, Karen, Chailyan, Gor, Hovakimyan, Armine, Antonyan, Tatevik, Kiani Shabestari, Sepideh, Petrushina, Irina, Davtyan, Hayk, Cribbs, David H., Blurton-Jones, Mathew, Masliah, Eliezer, Agadjanyan, Michael G., Ghochikyan, Anahit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181659/ https://www.ncbi.nlm.nih.gov/pubmed/35682759 http://dx.doi.org/10.3390/ijms23116080 |
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