Smaller, Stronger, More Stable: Peptide Variants of a SARS-CoV-2 Neutralizing Miniprotein

Based on the structure of a de novo designed miniprotein (LCB1) in complex with the receptor binding domain (RBD) of the SARS-CoV-2 spike protein, we have generated and characterized truncated peptide variants of LCB1, which present only two of the three LCB1 helices, and which fully retained the vi...

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Detalles Bibliográficos
Autores principales: Weißenborn, Lucas, Richel, Elie, Hüseman, Helena, Welzer, Julia, Beck, Silvan, Schäfer, Simon, Sticht, Heinrich, Überla, Klaus, Eichler, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181698/
https://www.ncbi.nlm.nih.gov/pubmed/35682988
http://dx.doi.org/10.3390/ijms23116309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181698/
https://www.ncbi.nlm.nih.gov/pubmed/35682988
http://dx.doi.org/10.3390/ijms23116309

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